Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | MITF | O75030 | 1/20 | 0.67 |
| ▸ | XBP1 | P17861 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.60 |
| ▸ | RELA | Q04206 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | SFN | P31947 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.52 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722714 | 0.85 | RAB9A (0.64) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL9722680 | 0.83 | RAB9A (0.77) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL27374898 | 0.81 | NPC1 (1.00) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL9722691 | 0.79 | NPC1 (0.80) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL7009383 | 0.78 | NPC1 (0.64) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL9722686 | 0.77 | RAB9A (0.73) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL28815524 | 0.76 | OGG1 (0.59) | NPC1RAB9ATP53HPGDSMN1; SMN2 | |
| SCHEMBL9722705 | 0.75 | RAB9A (0.71) | NPC1RAB9ATP53HPGDPKM | |
| Hydrochloric Acid SCHEMBL7014888 | 0.75 | GAA (0.69) | NPC1RAB9ATP53HPGDPKM | |
| SCHEMBL969459 | 0.74 | NPC1 (0.71) | NPC1RAB9ATP53HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139564-A | Applying postemergence | PARK SANG W (KR) | 1992-08-18 | — | — | US | claimed |
| US-5139564-A | Applying postemergence | PARK SANG W (KR) | 1992-08-18 | — | — | US | disclosed |