Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | PPARD | Q03181 | 6/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30965304 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL30462352 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL29010718 | 1.00 | TSHR (0.67) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL28881161 | 0.97 | LMNA (0.65) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL6421779 | 0.91 | GPR84 (0.73) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL7103373 | 0.90 | TSHR (0.60) | TSHRLMNANFKB1PMP22ALDH1A1 | |
| SCHEMBL9901485 | 0.89 | GPR84 (0.67) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL29002015 | 0.89 | GPR84 (0.74) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| Dodecanoate SCHEMBL27783434 | 0.89 | GPR84 (0.74) | TSHRLMNAALDH1A1GPR84FFAR1 | |
| SCHEMBL31070280 | 0.88 | LMNA (0.59) | TSHRLMNANFKB1PMP22ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300232-B1 | SURFACE TREATMENT OF POLYOLEFIN OBJECTS | DSM N.V. (NL) | 1992-05-20 | — | — | EP | disclosed |
| US-4963299-A | USING FREE RADICALS | STAMICARBON B.V. (NL) | 1990-10-16 | — | — | US | disclosed |
| EP-0300232-A1 | Surface treatment of polyolefin objects | DSM N.V. (NL) | 1989-01-25 | — | — | EP | disclosed |