⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249622 | 0.88 | — | — | |
| SCHEMBL11547685 | 0.84 | SQLE (0.32) | — | |
| SCHEMBL11547687 | 0.84 | SQLE (0.32) | — | |
| SCHEMBL11545443 | 0.75 | KMT2A (0.43) | — | |
| SCHEMBL11545440 | 0.75 | KMT2A (0.43) | — | |
| SCHEMBL11459018 | 0.75 | CES2 (0.32) | — | |
| SCHEMBL11706727 | 0.74 | FNTA (0.38) | — | |
| SCHEMBL11866879 | 0.74 | — | — | |
| SCHEMBL11866888 | 0.74 | — | — | |
| SCHEMBL11706722 | 0.74 | FNTA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2532390-B1 | Pharmaceutical composition for liver diseases. | MD BIOALPHA CO LTD (KR) | 2016-08-17 | — | — | EP | disclosed |
| US-9066922-B2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO., LTD. (KR) | 2015-06-30 | — | — | US | disclosed |
| US-20130245111-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OR PREVENTION OF DISEASES INVOLVING OBESITY, DIABETES, METABOLIC SYNDROME, NEURO-DEGENERATIVE DISEASES AND MITOCHONDRIA DYSFUNCTION DISEASES | KT & G CO., LTD. (KR) | 2013-09-19 | — | — | US | disclosed |
| CN-103249762-A | Addition-curable metallosiloxane compound | DAICEL CORP | 2013-08-14 | — | — | CN | disclosed |
| EP-1848432-B1 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO LTD (KR) | 2013-07-17 | — | — | EP | disclosed |
| US-8466141-B2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | MD BIOALPHA CO., LTD. (KR) | 2013-06-18 | — | — | US | disclosed |
| EP-2532389-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532390-A2 | Pharmaceutical composition for obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| EP-2532388-A2 | Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases | Md Bioalpha Co., Ltd. (KR) | 2012-12-12 | — | — | EP | disclosed |
| US-20120114714-A1 | METHOD FOR THE TREATMENT AND PREVENTION OF ERECTILE DYSFUNCTION | KWAK TAEHWAN (KR) | 2012-05-10 | — | — | US | disclosed |
| US-5374629-A | A triene steroids as anticarcinogenic agents, treating skin disorders | LEO PHARMACEUTICAL PRODUCTS LTD. A/S LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1994-12-20 | — | — | US | disclosed |
| EP-0522013-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-11-23 | — | — | EP | disclosed |
| EP-0538297-A1 | ANTIVIRAL TETRAHYDROIMIDAZO 1,4]BENZODIAZEPIN-2-(THIO)ONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-04-28 | — | — | EP | disclosed |
| EP-0522013-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992000979-A1 | ANTIVIRAL TETRAHYDROIMIDAZO[1,4]BENZODIAZEPIN-2-(THIO)ONES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-01-23 | — | — | WO | disclosed |
| CN-1057840-A | New antiviral imidazolidine is [1,4] benzodiazepine-2-(sulphur) ketone also | JANSSEN PHARMACEUTICA NV (BE) | 1992-01-15 | — | — | CN | disclosed |
| WO-1991015475-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1991-10-17 | — | — | WO | disclosed |
| US-4206140-A | INSECTICIDES, ANTHELMINTICS | ROUSSEL UCLAF (FR) | 1980-06-03 | — | — | US | disclosed |
| US-4101574-A | Cyclopropanecarboxylic acid chlorides | ROUSSEL UCLAF (FR) | 1978-07-18 | — | — | US | disclosed |
| US-3997586-A | Cyclopropanecarboxylic acids and esters | ROUSSEL-UCLAF (FR) | 1976-12-14 | — | — | US | disclosed |