Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722807 | 0.72 | HTT (0.44) | BACE1 | |
| SCHEMBL9722805 | 0.72 | NR4A2 (0.47) | BACE1KDM4EMAPK1ALDH1A1PKM | |
| SCHEMBL23458524 | 0.70 | CACNA1H (0.38) | MKNK1MKNK2NOS3NOS2PTPN5 | |
| SCHEMBL5027281 | 0.68 | MAP4K4 (0.54) | — | |
| SCHEMBL29728013 | 0.68 | MAP4K4 (0.54) | — | |
| SCHEMBL5314200 | 0.68 | NR4A2 (0.56) | EPHX2SCN4ABACE1CDK2MKNK2 | |
| SCHEMBL14666984 | 0.67 | KDM4E (0.48) | EPHX2SCN4ABACE1CCNE2CCNA2 | |
| SCHEMBL29742208 | 0.67 | BACE1 (0.45) | EPHX2SCN4ABACE1CCNE2CCNA2 | |
| SCHEMBL7572616 | 0.67 | BACE1 (0.45) | EPHX2SCN4ABACE1CCNE2CCNA2 | |
| SCHEMBL23935164 | 0.67 | BACE1 (0.45) | EPHX2SCN4ABACE1CCNE2CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |