Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9722805 | 0.76 | NR4A2 (0.47) | HTTBACE1BCHEACHEGRIN1 | |
| SCHEMBL9722741 | 0.76 | MAPT (0.43) | BACE1BCHEACHEGRIN1GRIN2A | |
| SCHEMBL18074685 | 0.76 | RXFP1 (0.39) | HTTPDPK1JAK2TYMSCHEK1 | |
| SCHEMBL9722778 | 0.72 | CYP1A2 (0.47) | BCHEACHEGRIN1GRIN2ATYMS | |
| SCHEMBL9722811 | 0.72 | EPHX2 (0.47) | BACE1 | |
| SCHEMBL23067988 | 0.72 | HTT (0.41) | HTTPDPK1JAK2CHEK1PIM1 | |
| SCHEMBL4025561 | 0.70 | KDM4E (0.45) | HTTPDPK1BACE1ACHEADORA2A | |
| SCHEMBL8063590 | 0.69 | ALDH1A1 (0.46) | NT5E | |
| SCHEMBL10943121 | 0.69 | SLC2A1 (0.45) | HTT | |
| SCHEMBL23068046 | 0.69 | CASP3 (0.37) | HTTCHEK1PIM1AKT1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4456668-A | DYE BLEACH, TEXTILE DYES | CIBA GEIGY AG (CH) | 1984-06-26 | — | — | US | disclosed |
| EP-0040171-B1 | AZO DYESTUFFS, METHODS FOR THEIR PREPARATION AND THEIR USE AS COLOURING AGENTS IN THE SILVER DYESTUFF BLEACHING PROCESS | CIBA-GEIGY AG (CH) | 1984-03-21 | — | — | EP | disclosed |
| US-4409143-A | TEXTILES, PHOTOGRAPHY | CIBA-GEIGY AG (CH) | 1983-10-11 | — | — | US | disclosed |
| EP-0083009-A1 | Dispersion dyestuffs | BASF Aktiengesellschaft (DE) | 1983-07-06 | — | — | EP | disclosed |
| EP-0040171-A2 | Azo dyestuffs, methods for their preparation and their use as colouring agents in the silver dyestuff bleaching process | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |
| US-4234482-A | Substituted 3-carbalkoxy 4-alkylamino-azobenzene compound as disperse dyestuffs for synthetic fibers | PRODUITS CHIMIQUES UGINE KUHLMANN SERVICE PROPRIETE INDUSTRIELLE (FR) | 1980-11-18 | — | — | US | disclosed |