Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000457 | 0.86 | AOC3 (0.43) | SIGMAR1POLBALDH1A1MAPTHTR2A | |
| SCHEMBL574731 | 0.83 | SIGMAR1 (0.41) | CSNK1ESIGMAR1POLBALDH1A1MAPT | |
| SCHEMBL9151258 | 0.81 | SLC6A2 (0.43) | MAPT | |
| SCHEMBL18979255 | 0.81 | HTR2A (0.41) | CSNK1ESIGMAR1POLBALDH1A1MAPT | |
| SCHEMBL3791480 | 0.81 | HTR2A (0.41) | CSNK1ESIGMAR1POLBALDH1A1MAPT | |
| SCHEMBL9158423 | 0.80 | SLC6A2 (0.43) | MAPT | |
| SCHEMBL9154911 | 0.80 | SLC6A2 (0.43) | MAPT | |
| SCHEMBL16293299 | 0.80 | SIGMAR1 (0.39) | CSNK1ESIGMAR1POLBALDH1A1MAPT | |
| SCHEMBL15758656 | 0.80 | KCNH2 (0.40) | CSNK1ESIGMAR1POLBALDH1A1MAPT | |
| SCHEMBL9153172 | 0.80 | RARB (0.46) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108595-A | Rehydroxylating with water and hydrogen fluoride or a basic activator | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-28 | — | — | US | disclosed |
| US-5032266-A | Chromatography | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-16 | — | — | US | disclosed |
| US-4874518-A | CHROMATOGRAPHY | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-17 | — | — | US | disclosed |