SCHEMBL18979255

SCHEMBL18979255

CCCCCCC(c1ccccc1)[Si](Cl)(Cl)Cl

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.41
CSNK1E P49674 1/20 0.41
CYP19A1 P11511 3/20 0.40
OPRM1 P35372 2/20 0.40
OPRD1 P41143 2/20 0.40
OPRK1 P41145 2/20 0.40
OPRL1 P41146 2/20 0.40
NAAA Q02083 2/20 0.40
SIGMAR1 Q99720 1/20 0.40
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP1 P03956 1/20 0.39
MMP3 P08254 1/20 0.39
MMP14 P50281 1/20 0.39
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
KCNH2 Q12809 2/20 0.38
ASAH1 Q13510 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791480 1.00 HTR2A (0.41) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL574731 0.98 SIGMAR1 (0.41) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL18979305 0.93 POLB (0.41) HTR2ACYP19A1OPRM1OPRD1OPRK1
SCHEMBL3444925 0.85 AOC3 (0.42) HTR2ACYP19A1SIGMAR1ALDH1A1POLB
SCHEMBL9722923 0.81 CSNK1E (0.42) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL18979315 0.79 HTR2A (0.40) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL9398133 0.79 HTR2A (0.40) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL9395955 0.79 HTR2A (0.40) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL18979277 0.79 HTR2A (0.40) HTR2ACSNK1ECYP19A1OPRM1OPRD1
SCHEMBL9398012 0.79 HTR2A (0.40) HTR2ACSNK1ECYP19A1OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME UBE INDUSTRIES, LTD. (JP) 2018-08-02 US disclosed
EP-3181569-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK CONTAINING SAME, AND ORGANIC ELECTRONIC DEVICE USING SAME UBE Industries, Ltd. (JP) 2017-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180219160-A1 BENZOBIS(THIADIAZOLE) DERIVATIVE, INK COMPRISING THE SAME, AND ORGANIC ELECTRONIC DEVICE USING THE SAME IKZF3, HELZ, TEC HTR2A 4267/4885CSNK1E 1310/4885CYP19A1 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.