Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811445 | 0.87 | ALDH1A1 (0.43) | CA1CA2ALDH1A1TRPA1KDM4E | |
| Phenol SCHEMBL9576413 | 0.83 | TDP1 (0.52) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL4724883 | 0.76 | CA12 (0.44) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL27824277 | 0.75 | CA12 (0.61) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL541839 | 0.73 | ALDH1A1 (0.74) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL8154763 | 0.73 | ALDH1A1 (0.74) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL8421097 | 0.73 | CA12 (0.58) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28870687 | 0.73 | CA12 (0.65) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL28170579 | 0.72 | TRPA1 (0.50) | TDP1CA12CA1CA2GLA | |
| Phenol SCHEMBL8157908 | 0.71 | TDP1 (0.48) | TDP1CA12CA1CA2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468162-A1 | Modified polyphenylene ether based thermoplastic moulding compositions | HÜLS AKTIENGESELLSCHAFT (DE) | 1992-01-29 | — | — | EP | claimed |