Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | APP | P05067 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL11535284 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL211558 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Hydroquinone SCHEMBL9498831 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Hydroquinone SCHEMBL9653092 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL6288836 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL121335 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL6547631 | 1.00 | ALDH1A1 (1.00) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL4435803 | 0.98 | ALDH1A1 (0.95) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL9137889 | 0.98 | ALDH1A1 (0.95) | ALDH1A1CYP3A4RECQLHSD17B10TP53 | |
| Sulfuric Acid SCHEMBL8389543 | 0.98 | ALDH1A1 (0.95) | ALDH1A1CYP3A4RECQLHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5100761-A | Acylhydrazine compounds, high contrast, storage stability | FUJI PHOTO FILM CO., LTD. (JP) | 1992-03-31 | — | — | US | disclosed |