Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 3/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | PRKACA | P17612 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 3/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.43 |
| ▸ | PLK4 | O00444 | 2/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.43 |
| ▸ | SGK2 | Q9HBY8 | 2/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6243938 | 0.76 | PRKCZ (0.72) | PRKCZAURKBCYP2B6FLT3TNF | |
| SCHEMBL29501875 | 0.76 | PRKCZ (0.72) | PRKCZAURKBCYP2B6FLT3TNF | |
| SCHEMBL12074301 | 0.73 | PRKCZ (0.73) | PRKCZAURKBCYP2B6FLT3TNF | |
| SCHEMBL30711433 | 0.73 | TNF (0.55) | PRKCZAURKACDK1PIM1PRKACA | |
| SCHEMBL28147703 | 0.73 | TNF (0.55) | PRKCZAURKACDK1PIM1PRKACA | |
| SCHEMBL9825010 | 0.71 | CYP2A6 (0.41) | CYP2B6CYP2A6MAPK1TNFKDM4E | |
| SCHEMBL9723383 | 0.70 | PRKCZ (0.46) | PRKCZAURKACDK1PIM1PRKACA | |
| SCHEMBL14748847 | 0.69 | CYP2A6 (0.52) | CYP2B6CYP2A6FGFR1MAPK1KDM4E | |
| SCHEMBL17981126 | 0.68 | TDP1 (0.50) | PRKCZAURKACDK1PIM1PRKACA | |
| SCHEMBL7816489 | 0.68 | PRKCZ (0.47) | PRKCZAURKACDK1PIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4963616-A | N-HETERO MACROMOLECULAR, RIGID CHAIN OR LADDER POLYMERS COM-PLEXED WITH LEWIS ACIDS | HONEYWELL INC. (US) | 1990-10-16 | — | — | US | claimed |
| US-4945156-A | DECOMPLEXING POLYMER-LEWIS ACID COMPLEX TO REGENERATE | HONEYWELL INC. (US) | 1990-07-31 | — | — | US | claimed |
| CN-110730686-A | Sorbent-loaded fibers for high temperature adsorption processes | 乔治洛德方法研究和开发液化空气有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-110650799-A | Sorbent-loaded beads for high temperature adsorption processes | 乔治洛德方法研究和开发液化空气有限公司 | 2020-01-03 | — | — | CN | disclosed |
| US-5114610-A | Lewis acids dissolved in aprotic organic solvents | HONEYWELL INC. (US) | 1992-05-19 | — | — | US | disclosed |
| US-4963616-A | N-HETERO MACROMOLECULAR, RIGID CHAIN OR LADDER POLYMERS COM-PLEXED WITH LEWIS ACIDS | HONEYWELL INC. (US) | 1990-10-16 | — | — | US | disclosed |
| US-4945156-A | DECOMPLEXING POLYMER-LEWIS ACID COMPLEX TO REGENERATE | HONEYWELL INC. (US) | 1990-07-31 | — | — | US | disclosed |