SCHEMBL9723229

SCHEMBL9723229

CCC(c1ccc(N)cc1)c1ccc(N)cc1.Nc1cccc(N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.48
CASP1 P29466 1/20 0.48
RECQL P46063 1/20 0.48
CYP19A1 P11511 3/20 0.42
TP53 P04637 1/20 0.41
CYP17A1 P05093 1/20 0.41
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.39
TSHR P16473 2/20 0.39
CPN1 P15169 1/20 0.39
CPB2 Q96IY4 1/20 0.39
BCHE P06276 1/20 0.38
TYR P14679 1/20 0.38
ACHE P22303 1/20 0.38
PDE4A P27815 1/20 0.37
ALDH1A1 P00352 3/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3697797 0.92 CPN1 (0.44) CYP3A4CASP1RECQLCYP19A1TP53
Benzene SCHEMBL28278798 0.89 TSHR (0.41) CYP3A4RECQLCYP17A1MAOAMAOB
SCHEMBL2913955 0.88 BCHE (0.41) CYP3A4CYP19A1CYP17A1TSHRCPN1
SCHEMBL48724 0.87 MAPT (0.42) CYP3A4RECQLCYP19A1TP53CYP17A1
SCHEMBL8100164 0.87 MAPT (0.42) CYP3A4RECQLCYP19A1TP53CYP17A1
SCHEMBL2914007 0.87 MAPT (0.42) CYP3A4RECQLCYP19A1TP53CYP17A1
SCHEMBL3049115 0.85 HTR2A (0.46) CYP3A4MAOAMAOBTSHRALDH1A1
SCHEMBL9402905 0.83 CPN1 (0.49) CYP3A4CASP1RECQLTP53MAOA
SCHEMBL3141683 0.82 ALDH1A1 (0.59) CYP3A4TP53MAOAMAOBTSHR
SCHEMBL10454608 0.82 CYP3A4 (0.42) CYP3A4CASP1MAOAMAOBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089560-A Fiber reinforced composites AMOCO CORPORATION (US) 1992-02-18 US disclosed
US-4977215-A CONTAINING EPOXY RESIN AMOCO CORPORATION (US) 1990-12-11 US disclosed
US-4977218-A FILLERS FOR EPOXY RESINS; COMPRESSIVE AND IMPACT STRENGTH AMOCO CORPORATION (US) 1990-12-11 US disclosed