Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14991180 | 1.00 | CYP19A1 (0.44) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL14991039 | 1.00 | CYP19A1 (0.44) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL14609552 | 0.93 | CYP19A1 (0.41) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13321805 | 0.93 | CYP19A1 (0.41) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13321802 | 0.87 | CYP19A1 (0.38) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL5548750 | 0.86 | EPHX1 (0.42) | CYP19A1EPHX1SMN1; SMN2MAPTSERPINE1 | |
| SCHEMBL13698877 | 0.83 | CYP19A1 (0.38) | CYP19A1SMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL16714026 | 0.82 | CYP19A1 (0.43) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9723249 | 0.82 | CYP19A1 (0.43) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL938461 | 0.82 | CYP19A1 (0.43) | CYP19A1EPHX1SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382940-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. | 2023-11-30 | — | — | US | disclosed |
| WO-2023168254-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | GILEAD SCIENCES, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| US-20130144080-A1 | PROCESS FOR OBTAINING A DIALKYL CARBONATE AND AN ALKYLENE GLYCOL | BASF SE (DE) | 2013-06-06 | — | — | US | disclosed |
| US-5098886-A | Mixing compounds to improve odor | INTERNATIONAL FLAVORS & FRAGRANCES INC., A CORP. OF NEW YORK | 1992-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382940-A1 | ANTIVIRAL COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | EIF2AK2, MAVS, ZC3HAV1 | CYP19A1 4401/4885EPHX1 2624/4885SMN1; SMN2 1294/4885 |
| US-20130144080-A1 | PROCESS FOR OBTAINING A DIALKYL CARBONATE AND AN ALKYLENE GLYCOL | AGL, GNE, ADH1C | CYP19A1 3252/4885EPHX1 3759/4885SMN1; SMN2 3303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.