Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049807 | 0.74 | PDK2 (0.46) | ELANEMAPTGAAMAOAMAOB | |
| SCHEMBL674648 | 0.73 | TDP2 (0.39) | ELANECYP2A6NPC1MAPK1CYP1A2 | |
| SCHEMBL9509313 | 0.73 | MAPT (0.45) | ELANEMAPTGAAMAOAMAOB | |
| SCHEMBL31547677 | 0.72 | TDP1 (0.52) | ELANEMAPTGAAMAOAMAOB | |
| SCHEMBL3043421 | 0.72 | TDP1 (0.52) | ELANEMAPTGAAMAOAMAOB | |
| SCHEMBL11729295 | 0.72 | ELANE (0.52) | ELANEMAPTGAATDP1CYP2A6 | |
| SCHEMBL29590360 | 0.72 | ELANE (0.52) | ELANEMAPTGAATDP1CYP2A6 | |
| SCHEMBL3285155 | 0.70 | ESR2 (0.63) | ELANEMAPTGAAMAOBCYP2A6 | |
| SCHEMBL11588315 | 0.70 | GAA (0.52) | ELANEMAPTGAAMAOAMAOB | |
| SCHEMBL24625661 | 0.69 | ELANE (0.45) | ELANEMAPTGAATDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162406-A | Containing hydroxyphenylalkylenyl isocyanurate, polyphenylene diphosphonite and ackylidene bisphenol | THE DOW CHEMICAL COMPANY (US) | 1992-11-10 | — | — | US | disclosed |
| EP-0036278-B1 | POLYPHENYLENE ETHER RESIN COMPOSITION OF IMPROVED HEAT STABILITY AND SHAPED ARTICLES THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-4427814-A | DIPHOSPHONITE STABILIZER | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1984-01-24 | — | — | US | disclosed |
| EP-0036278-A1 | Polyphenylene ether resin composition of improved heat stability and shaped articles thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1981-09-23 | — | — | EP | disclosed |