Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183219 | 0.81 | CHRNA7 (0.53) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL8828073 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL9575730 | 0.78 | ACACB (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL11405912 | 0.77 | MEN1 (0.48) | ALDH1A1SMN1; SMN2LMNAKMT2AMEN1 | |
| Isopropyl Alcohol SCHEMBL2167428 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPTHPGDSMN1; SMN2LMNA | |
| SCHEMBL2798093 | 0.76 | KMT2A (0.54) | MAPTLMNAKMT2A | |
| SCHEMBL17061315 | 0.75 | CA12 (0.48) | ALDH1A1MAPTSMN1; SMN2PTPN1KMT2A | |
| SCHEMBL17061317 | 0.75 | CA12 (0.48) | ALDH1A1MAPTSMN1; SMN2PTPN1KMT2A | |
| SCHEMBL17061359 | 0.75 | CA12 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL17061361 | 0.75 | CA12 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | claimed |
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | disclosed |