SCHEMBL8828073

SCHEMBL8828073

CO[Si](CCCOc1ccc(C=O)cc1)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
SMN1; SMN2 Q16637 4/20 0.57
MAPT P10636 3/20 0.57
LMNA P02545 3/20 0.57
HPGD P15428 2/20 0.57
CYP2A6 P11509 1/20 0.53
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
KDM4E B2RXH2 3/20 0.43
AHR P35869 1/20 0.43
FDPS P14324 1/20 0.42
ALDH1A3 P47895 1/20 0.41
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10890669 0.85 ALDH1A1 (0.55) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL8776463 0.83 CHRNA7 (0.51) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL4131738 0.83 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL14632314 0.82 MAPT (0.50) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL19214413 0.80 ALDH1A1 (0.76) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL10891841 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL28363157 0.80 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL5090074 0.80 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL8204708 0.80 ALDH1A1 (0.75) ALDH1A1SMN1; SMN2MAPTLMNAHPGD
SCHEMBL8551794 0.80 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2MAPTLMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114574090-B Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof 宁波集科威视讯有限公司 2022-11-04 CN claimed
CN-114574090-A Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof 宁波集科威视讯有限公司 2022-06-03 CN claimed
CN-102993389-B Optical intelligent silicagel surface molecularly imprinted microsphere and preparation method thereof UNIV CENTRAL SOUTH 2014-07-02 CN claimed
CN-102993389-A Optical intelligent silicagel surface molecularly imprinted microsphere and preparation method thereof UNIV CENTRAL SOUTH 2013-03-27 CN claimed
US-4645844-A Functionally substituted phenoxyalkyl alkoxysilanes and method for preparing same M&T CHEMICALS INC. (US) 1987-02-24 US claimed
CN-114574090-B Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof 宁波集科威视讯有限公司 2022-11-04 CN disclosed
CN-114574090-A Anti-dazzle and anti-scratch functional film for display and preparation method and application thereof 宁波集科威视讯有限公司 2022-06-03 CN disclosed
CN-102993389-B Optical intelligent silicagel surface molecularly imprinted microsphere and preparation method thereof UNIV CENTRAL SOUTH 2014-07-02 CN disclosed
CN-102993389-A Optical intelligent silicagel surface molecularly imprinted microsphere and preparation method thereof UNIV CENTRAL SOUTH 2013-03-27 CN disclosed
US-5676883-A FORMING SOL OF ALKOXYSILANE COMPOUND INCLUDING NONLINEAR OPTICAL COMPONENT, FORMING GEL, POLING, TRANSESTERIFYING ALKOXYSILANE TO FORM NONLINEAR OPTICAL COMPOSITION UNIVERSITY OF MASSACHUSETTS LOWELL (US) 1997-10-14 US disclosed
US-5433895-A Silicon-containing networked non-linear optical compositions UNIVERSITY OF MASSACHUSETTS LOWELL (US) 1995-07-18 US disclosed
US-4645844-A Functionally substituted phenoxyalkyl alkoxysilanes and method for preparing same M&T CHEMICALS INC. (US) 1987-02-24 US disclosed