Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9328737 | 0.86 | KMT2A (0.36) | AKR1B1HDAC4ALDH1A1TP53HTT | |
| SCHEMBL9326002 | 0.86 | POLB (0.51) | POLBCASP6AKR1B1HTTCYP1A2 | |
| SCHEMBL9329017 | 0.85 | AKR1B1 (0.42) | POLBCASP6AKR1B1HDAC4 | |
| SCHEMBL9723534 | 0.83 | AKR1B1 (0.37) | POLBCASP6AKR1B1HDAC4 | |
| SCHEMBL9327360 | 0.81 | POLB (0.44) | POLBCASP6AKR1B1ALDH1A1LMNA | |
| SCHEMBL9327155 | 0.79 | POLB (0.35) | POLBCASP6AKR1B1PKMALDH1A1 | |
| SCHEMBL1292158 | 0.79 | POLB (0.49) | POLBCASP6PKMSIRT1ALDH1A1 | |
| SCHEMBL9751997 | 0.75 | POLB (0.43) | POLBCASP6SIRT1ALDH1A1LMNA | |
| SCHEMBL9327296 | 0.74 | CYP1A2 (0.38) | PKMALDH1A1HTTCYP1A2CYP2C9 | |
| SCHEMBL9327109 | 0.74 | POLB (0.55) | POLBCASP6AKR1B1HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | claimed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | claimed |