Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326002 | 0.87 | POLB (0.51) | POLBCASP6AKR1B1GAA | |
| SCHEMBL9329074 | 0.86 | LPAR1 (0.39) | LMNALPAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9723392 | 0.81 | POLB (0.40) | POLBCASP6AKR1B1LMNAALDH1A1 | |
| SCHEMBL10472310 | 0.77 | POLB (0.47) | POLBCASP6AKR1B1LMNAMAOB | |
| SCHEMBL9329017 | 0.75 | AKR1B1 (0.42) | POLBCASP6AKR1B1MEN1KMT2A | |
| SCHEMBL9327155 | 0.75 | POLB (0.35) | POLBCASP6AKR1B1LMNAALDH1A1 | |
| SCHEMBL9327109 | 0.75 | POLB (0.55) | POLBCASP6AKR1B1MEN1KMT2A | |
| SCHEMBL9723534 | 0.74 | AKR1B1 (0.37) | POLBCASP6AKR1B1MEN1KMT2A | |
| SCHEMBL9751992 | 0.74 | POLB (0.46) | POLBCASP6AKR1B1LMNAMAOB | |
| SCHEMBL9325969 | 0.73 | ALDH1A1 (0.43) | AKR1B1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0403026-B1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DOWELANCO (US) | 1994-03-02 | — | — | EP | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |
| US-5071465-A | Preemergence; postemergence | THE DOW CHEMICAL COMPANY (US) | 1991-12-10 | — | — | US | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |