Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1704691 | 0.90 | HMGCR (1.00) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL7086384 | 0.82 | HMGCR (0.85) | HMGCRNR1I2GAAKMT2AMEN1 | |
| SCHEMBL9723334 | 0.80 | HMGCR (0.71) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL7083916 | 0.79 | HMGCR (0.80) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL7134552 | 0.77 | HMGCR (0.76) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL7084466 | 0.76 | HMGCR (0.74) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL6370947 | 0.73 | HMGCR (0.66) | HMGCRALDH1A1GAALMNATSHR | |
| Apomine SCHEMBL1648488 | 0.73 | HMGCR (1.00) | HMGCR | |
| Potassium SCHEMBL4892236 | 0.73 | HMGCR (0.61) | HMGCRNR1I2ALDH1A1GAALMNA | |
| SCHEMBL29234895 | 0.73 | HMGCR (0.65) | HMGCRNR1I2ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128331-A | Gen-diphosphonates | SYMPHAR S.A. (CH) | 1992-07-07 | — | — | US | disclosed |
| US-5043330-A | Antiinflammatory and hypotensive agents; antihyperlipemia | SYMPHAR S.A. (CH) | 1991-08-27 | — | — | US | disclosed |