SCHEMBL9723455

SCHEMBL9723455

Oc1ccc(C(=C(c2ccccc2)c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.70
CES2 O00748 1/20 0.64
ESR2 Q92731 4/20 0.61
CYP19A1 P11511 3/20 0.61
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
LMNA P02545 2/20 0.56
MAPT P10636 2/20 0.56
RAB9A P51151 2/20 0.56
CA12 O43570 3/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA3 P07451 3/20 0.56
CA4 P22748 3/20 0.56
CA9 Q16790 3/20 0.56
CA14 Q9ULX7 3/20 0.56
GLA P06280 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
MMP3 P08254 1/20 0.52
BCL2L1 Q07817 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68101 1.00 ESR1 (0.70) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL14354292 1.00 ESR1 (0.70) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL9891113 1.00 ESR1 (0.70) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL68100 1.00 ESR1 (0.70) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL17368206 0.92 RAB9A (0.68) ESR1CES2ESR2CYP19A1MEN1
Phenol SCHEMBL27779673 0.91 CA12 (0.69) ESR1CES2ESR2CYP19A1MEN1
Phenol SCHEMBL28483837 0.91 CA12 (0.69) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL24023120 0.88 ESR1 (0.61) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL19859193 0.88 ALOX15 (0.59) ESR1CES2ESR2CYP19A1MEN1
SCHEMBL19859420 0.88 ALOX15 (0.59) ESR1CES2ESR2CYP19A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112174785-B Fluorescent probe based on tetraphenylethylene derivative, preparation method and application thereof 扬州大学 2022-03-29 CN claimed
EP-4608895-A1 HIGH TEMPERATURE DIELECTRIC POLYMERS AND FILMS The Scripps Research Institute (US) 2025-09-03 EP disclosed
CN-116514689-B Activated alkyne-tetrastyrenesulfonic acid sodium salt molecule, preparation method and application thereof in high-throughput screening of antibiotics 南开大学 2025-04-18 CN disclosed
WO-2024091684-A1 POLYSULFATE AND POLYSULFONATE POLYMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO disclosed
WO-2024091684-A1 POLYSULFATE AND POLYSULFONATE POLYMERS THE SCRIPPS RESEARCH INSTITUTE (US) 2024-05-02 WO disclosed
CN-116514689-A Activated alkyne-tetrastyrenesulfonic acid sodium salt molecule, preparation method and application thereof in high-throughput screening of antibiotics 南开大学 2023-08-01 CN disclosed
CN-112174785-B Fluorescent probe based on tetraphenylethylene derivative, preparation method and application thereof 扬州大学 2022-03-29 CN disclosed
EP-0467847-A1 Polyarylene ether with tetraphenylethylene units CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed