Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671507 | 0.85 | L3MBTL1 (0.36) | L3MBTL1MAPTTDP1 | |
| SCHEMBL28489132 | 0.82 | SMN1; SMN2 (0.38) | L3MBTL1MAPTTDP1 | |
| SCHEMBL2974066 | 0.81 | L3MBTL1 (0.37) | L3MBTL1MAPT | |
| SCHEMBL6776792 | 0.79 | PTPN1 (0.35) | — | |
| SCHEMBL7997625 | 0.79 | PTPN1 (0.38) | — | |
| SCHEMBL164522 | 0.78 | — | — | |
| SCHEMBL3210792 | 0.78 | BACE1 (0.33) | MAPT | |
| SCHEMBL28843377 | 0.78 | TDP1 (0.33) | L3MBTL1TDP1 | |
| SCHEMBL29027260 | 0.78 | — | — | |
| SCHEMBL9327083 | 0.78 | CA1 (0.38) | L3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100482647-C | Pyrazole derivatives useful as COX-I inhibitors | ASTELLAS PHARMACY CO LTD (JP) | 2009-04-29 | — | — | CN | disclosed |
| CN-1717393-A | Pyrazole derivatives as COX-1 inhibitors | FUJISAWA PHARMACEUTICAL CO (JP) | 2006-01-04 | — | — | CN | disclosed |
| US-5158597-A | Herbicidal 12-substituted 12H-dibenzo[d,g]dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1992-10-27 | — | — | US | disclosed |