SCHEMBL7997625

SCHEMBL7997625

COCOc1[c]cccc1C

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.38
ALDH1A1 P00352 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674059 0.84 TSHR (0.31) ALDH1A1
SCHEMBL6776792 0.81 PTPN1 (0.35) PTPN1
SCHEMBL2456321 0.80 NQO1 (0.36) ALDH1A1GLA
SCHEMBL9723567 0.79 L3MBTL1 (0.31)
SCHEMBL28843377 0.79 TDP1 (0.33)
SCHEMBL29027260 0.79
SCHEMBL3210792 0.79 BACE1 (0.33) PTPN1ALDH1A1
SCHEMBL9327083 0.79 CA1 (0.38) PTPN1ALDH1A1
SCHEMBL8009349 0.78 ALDH1A1 (0.31) ALDH1A1GLA
SCHEMBL275849 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6048863-A SEXUAL DISORDERS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2000-04-11 US disclosed