Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | PDE5A | O76074 | 2/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3565552 | 0.94 | ALDH1A1 (0.74) | ALDH1A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL2020050 | 0.86 | CNR1 (0.57) | ALDH1A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL31588918 | 0.86 | CNR1 (0.57) | ALDH1A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL8466368 | 0.86 | CNR1 (0.57) | ALDH1A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL31429954 | 0.84 | SMN1; SMN2 (0.64) | ALDH1A1LMNAMAPTSMN1; SMN2PDE5A | |
| SCHEMBL11976312 | 0.83 | PDE5A (0.57) | ALDH1A1LMNAPDE5ANR3C2 | |
| SCHEMBL31429952 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1LMNAMAPTSMN1; SMN2PDE5A | |
| SCHEMBL31429950 | 0.82 | SMN1; SMN2 (0.61) | ALDH1A1LMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL11976311 | 0.82 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTKDM4ENPC1 | |
| SCHEMBL2021434 | 0.81 | CNR1 (0.52) | ALDH1A1LMNAMAPTKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091405-A | Insecticidal pyrazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0330678-B1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0330678-A1 | INSECTICIDAL PYRAZOLINES. | DU PONT (US) | 1989-09-06 | — | — | EP | disclosed |
| WO-1988006583-A1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |