Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723620 | 0.94 | ALDH1A1 (0.65) | ALDH1A1LMNASMN1; SMN2ACHECNR1 | |
| SCHEMBL31429954 | 0.91 | SMN1; SMN2 (0.64) | ALDH1A1LMNASMN1; SMN2ACHEMAPT | |
| SCHEMBL31429950 | 0.88 | SMN1; SMN2 (0.61) | ALDH1A1LMNASMN1; SMN2ACHECNR1 | |
| SCHEMBL31429952 | 0.88 | SMN1; SMN2 (0.61) | ALDH1A1LMNASMN1; SMN2ACHEMAPT | |
| SCHEMBL31429972 | 0.87 | SMN1; SMN2 (0.60) | ALDH1A1LMNASMN1; SMN2ACHEMAPT | |
| SCHEMBL31429978 | 0.86 | ALDH1A1 (0.57) | ALDH1A1LMNASMN1; SMN2ACHECNR1 | |
| SCHEMBL31429953 | 0.85 | SMN1; SMN2 (0.58) | ALDH1A1LMNASMN1; SMN2ACHEMAPT | |
| SCHEMBL31429935 | 0.84 | SMN1; SMN2 (0.57) | ALDH1A1LMNASMN1; SMN2ACHEMAPT | |
| SCHEMBL1023193 | 0.82 | CNR1 (0.58) | ALDH1A1LMNACNR1CNR2PDE5A | |
| SCHEMBL31429966 | 0.82 | SMN1; SMN2 (0.59) | ALDH1A1LMNASMN1; SMN2ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119698496-A | Electrochemical synthesis of pyrazolines and pyrazoles | 拜耳公司 | 2025-03-25 | — | — | CN | disclosed |
| US-20110053983-A1 | (5R)-1,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXAMIDINE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | ABBOTT HEALTHCARE PRODUCTS B.V. (NL) | 2011-03-03 | — | — | US | disclosed |
| US-7745476-B2 | 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity | SOLVAY PHARMACEUTICALS B.V. (NL) | 2010-06-29 | — | — | US | disclosed |
| EP-1713475-B1 | 1,3,5-TRISUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | SOLVAY PHARM BV (NL) | 2008-07-30 | — | — | EP | disclosed |
| EP-1713475-A1 | 1,3,5-TRISUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | Solvay Pharmaceuticals B.V. (NL) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005074920-A1 | 1,3,5-TRISUBSTITUTED 4,5-DIHYDRO-1H-PYRAZOLE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | SOLVAY PHARMACEUTICALS B.V. (NL) | 2005-08-18 | — | — | WO | disclosed |
| US-20050171179-A1 | 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity | SOLVAY PHARMACEUTICALS B.V. | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053983-A1 | (5R)-1,5-DIARYL-4,5-DIHYDRO-1H-PYRAZOLE-3-CARBOXAMIDINE DERIVATIVES HAVING CB1-ANTAGONISTIC ACTIVITY | CNR1, CNR2, HTR5A | ALDH1A1 1089/4885LMNA 4143/4885SMN1; SMN2 2198/4885 |
| US-20050171179-A1 | 1,3,5-trisubstituted 4,5-dihydro-1H-pyrazole derivatives having CB1-antagonistic activity | CNR2, CNR1, TBXA2R | ALDH1A1 1262/4885LMNA 4581/4885SMN1; SMN2 4253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.