⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146416 | 0.83 | — | — | |
| SCHEMBL297916 | 0.71 | TSHR (0.59) | — | |
| SCHEMBL5886448 | 0.69 | TSHR (0.43) | — | |
| SCHEMBL27926059 | 0.68 | TSHR (0.56) | — | |
| SCHEMBL9723633 | 0.68 | — | — | |
| SCHEMBL2709332 | 0.67 | TSHR (0.48) | — | |
| SCHEMBL11799794 | 0.67 | — | — | |
| SCHEMBL16048299 | 0.66 | TSHR (0.53) | — | |
| SCHEMBL20565358 | 0.66 | TSHR (0.53) | — | |
| SCHEMBL11510451 | 0.66 | TSHR (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501424-A1 | Transparent thermoplastic moulding composition, process for its preparation and its use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-02 | — | — | EP | disclosed |