Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.76 |
| ▸ | CA2 | P00918 | 6/20 | 0.76 |
| ▸ | CA7 | P43166 | 5/20 | 0.76 |
| ▸ | CA4 | P22748 | 4/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723676 | 1.00 | CA1 (0.76) | CA1CA2CA7CA4MAPT | |
| SCHEMBL9723609 | 0.88 | CA1 (0.62) | CA1CA2CA7CA4MAPT | |
| SCHEMBL9723601 | 0.88 | CA1 (0.62) | CA1CA2CA7CA4MAPT | |
| SCHEMBL2174834 | 0.81 | CA2 (0.54) | CA1CA2CA7CA4MAPT | |
| SCHEMBL2174838 | 0.81 | CA2 (0.54) | CA1CA2CA7CA4MAPT | |
| SCHEMBL4104755 | 0.80 | CA1 (0.53) | CA1CA2CA7CA4MAPT | |
| SCHEMBL9068333 | 0.80 | CA1 (0.52) | CA1CA2CA7CA4MAPT | |
| SCHEMBL15047078 | 0.80 | CA1 (0.52) | CA1CA2CA7CA4MAPT | |
| SCHEMBL9068078 | 0.80 | CA1 (0.52) | CA1CA2CA7CA4MAPT | |
| SCHEMBL9633483 | 0.79 | CA1 (0.51) | CA1CA2CA7CA4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091405-A | Insecticidal pyrazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0330678-B1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-24 | — | — | EP | disclosed |
| EP-0330678-A1 | INSECTICIDAL PYRAZOLINES. | DU PONT (US) | 1989-09-06 | — | — | EP | disclosed |
| WO-1988006583-A1 | INSECTICIDAL PYRAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-09-07 | — | — | WO | disclosed |