Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.62 |
| ▸ | CA2 | P00918 | 5/20 | 0.62 |
| ▸ | CA7 | P43166 | 5/20 | 0.62 |
| ▸ | CA4 | P22748 | 4/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | RHOC | P08134 | 2/20 | 0.47 |
| ▸ | RHOA | P61586 | 2/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723601 | 1.00 | CA1 (0.62) | CA1CA2CA7CA4CNR1 | |
| SCHEMBL9723675 | 0.88 | CA1 (0.76) | CA1CA2CA7CA4CNR1 | |
| SCHEMBL9723676 | 0.88 | CA1 (0.76) | CA1CA2CA7CA4CNR1 | |
| SCHEMBL17803166 | 0.79 | EPHX2 (0.49) | EPHX2MEN1GAAMAPTKMT2A | |
| SCHEMBL17803167 | 0.79 | EPHX2 (0.49) | EPHX2MEN1GAAMAPTKMT2A | |
| SCHEMBL4104729 | 0.78 | RHOC (0.51) | CNR1EPHX2CNR2P2RX1P2RX4 | |
| SCHEMBL4104726 | 0.78 | RHOC (0.51) | CNR1EPHX2CNR2P2RX1P2RX4 | |
| SCHEMBL4109459 | 0.77 | CNR2 (0.51) | CNR1EPHX2CNR2P2RX1P2RX4 | |
| SCHEMBL4109462 | 0.77 | CNR2 (0.51) | CNR1EPHX2CNR2P2RX1P2RX4 | |
| SCHEMBL4922162 | 0.77 | EPHX2 (0.81) | CA1CA2CNR1EPHX2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091405-A | Insecticidal pyrazolines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-02-25 | — | — | US | disclosed |