Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533713 | 0.93 | LMNA (0.50) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL4334155 | 0.87 | LMNA (0.55) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL17797792 | 0.83 | CA1 (0.55) | LMNACA12CA1CA2CA7 | |
| SCHEMBL3320116 | 0.80 | CA12 (0.68) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL28927209 | 0.78 | CA1 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10880499 | 0.78 | LMNA (0.59) | LMNACYP1A2CYP3A4MAOACA12 | |
| SCHEMBL9004307 | 0.77 | CA1 (0.48) | LMNACA12CA1CA2CA7 | |
| SCHEMBL17824411 | 0.77 | MAPT (0.49) | LMNACA12CA1CA2CA7 | |
| SCHEMBL26102695 | 0.76 | CA12 (0.52) | LMNACA12CA1CA2CA7 | |
| SCHEMBL10885498 | 0.76 | PDCD1 (0.49) | LMNACYP1A2CYP3A4MAOACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102448-A | Hot melt of solid ink composition | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-04-07 | — | — | US | disclosed |
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |