Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690104 | 1.00 | TERT (0.49) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9723756 | 1.00 | TERT (0.49) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9723781 | 1.00 | TERT (0.49) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL9723747 | 1.00 | TERT (0.49) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL11690113 | 1.00 | TERT (0.49) | TERTPTPN1PPARGPPARDPPARA | |
| SCHEMBL8972961 | 0.91 | L3MBTL1 (0.53) | MAPTCYP2C19KMT2APOLBMEN1 | |
| SCHEMBL8972169 | 0.91 | L3MBTL1 (0.53) | MAPTCYP2C19KMT2APOLBMEN1 | |
| SCHEMBL8972695 | 0.91 | L3MBTL1 (0.53) | MAPTCYP2C19KMT2APOLBMEN1 | |
| SCHEMBL8972586 | 0.91 | L3MBTL1 (0.53) | MAPTCYP2C19KMT2APOLBMEN1 | |
| SCHEMBL8972946 | 0.91 | L3MBTL1 (0.53) | MAPTCYP2C19KMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | claimed |
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |