Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25630960 | 0.81 | FAAH (0.45) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20172629 | 0.78 | FAAH (0.42) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL11399712 | 0.77 | KMT2A (0.47) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22053528 | 0.75 | FAAH (0.40) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL24411467 | 0.73 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22057652 | 0.73 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL21913825 | 0.73 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22053587 | 0.73 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL14217912 | 0.73 | FAAH (0.50) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL97000 | 0.71 | KMT2A (0.50) | FAAHPHGDHMGLLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169958-A | Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |