Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24411467 | 0.84 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20932119 | 0.84 | ALDH1A1 (0.39) | LMNAKMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13119958 | 0.81 | NPSR1 (0.40) | L3MBTL1KMT2AMEN1HTTPOLB | |
| SCHEMBL20172629 | 0.81 | FAAH (0.42) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL25630960 | 0.80 | FAAH (0.45) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22053587 | 0.80 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL18436868 | 0.80 | FAAH (0.39) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL12956820 | 0.80 | FAAH (0.40) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL20341419 | 0.79 | FAAH (0.42) | FAAHPHGDHMGLLCA12CA1 | |
| SCHEMBL22648602 | 0.78 | HSD17B2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |