Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703588 | 0.86 | DHODH (0.53) | DHODHHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL27792518 | 0.86 | KMT2A (0.57) | HTTSMN1; SMN2GAAKMT2AALDH1A1 | |
| SCHEMBL28619132 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL1336621 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL27934857 | 0.85 | ALDH1A1 (0.57) | SMN1; SMN2GAAKMT2AALDH1A1MEN1 | |
| SCHEMBL5694725 | 0.84 | NPSR1 (0.50) | DHODHHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL5694726 | 0.84 | NPSR1 (0.50) | DHODHHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL23842604 | 0.83 | DHODH (0.45) | DHODHHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL9364429 | 0.83 | DHODH (0.45) | DHODHHTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL9364432 | 0.83 | DHODH (0.45) | DHODHHTTSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169958-A | Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |