Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364432 | 1.00 | DHODH (0.45) | DHODHHTTGAASMN1; SMN2FNTA | |
| SCHEMBL9363953 | 0.88 | SMN1; SMN2 (0.47) | GAASMN1; SMN2FNTAFNTBLMNA | |
| SCHEMBL9363956 | 0.88 | SMN1; SMN2 (0.47) | GAASMN1; SMN2FNTAFNTBLMNA | |
| SCHEMBL9364404 | 0.87 | ALDH1A1 (0.51) | GAASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL9364405 | 0.87 | ALDH1A1 (0.51) | GAASMN1; SMN2LMNAALDH1A1KDM4E | |
| SCHEMBL5694726 | 0.85 | NPSR1 (0.50) | DHODHHTTGAASMN1; SMN2FNTA | |
| SCHEMBL5694725 | 0.85 | NPSR1 (0.50) | DHODHHTTGAASMN1; SMN2FNTA | |
| SCHEMBL9360086 | 0.84 | ALDH1A1 (0.48) | LMNACYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL9360090 | 0.84 | ALDH1A1 (0.48) | LMNACYP1A2CYP3A4ALDH1A1MAPT | |
| SCHEMBL9723849 | 0.83 | DHODH (0.50) | DHODHHTTGAASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393713-B1 | Process for the preparation of N-substituted maleimides | TOSOH CORP (JP) | 1994-06-29 | — | — | EP | disclosed |
| US-5087705-A | Heating N-substituted maleamic acid monoester in presence of acid catalyst | SHIN-DAIKYOWA PETROCHEMICAL CO., LTD. (JP) | 1992-02-11 | — | — | US | disclosed |
| EP-0393713-A1 | Process for the preparation of N-substituted maleimides | Tosoh Corporation (JP) | 1990-10-24 | — | — | EP | disclosed |