Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9723882 | 1.00 | MAPT (0.49) | MAPTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7055382 | 0.87 | MAPT (0.47) | MAPTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL7055390 | 0.87 | MAPT (0.47) | MAPTTDP1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2706971 | 0.83 | TDP1 (0.51) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL9723904 | 0.83 | ALDH1A1 (0.54) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL9723906 | 0.83 | ALDH1A1 (0.54) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL9667415 | 0.80 | CYP3A4 (0.50) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL522136 | 0.79 | KMT2A (0.59) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL17434551 | 0.79 | TDP1 (0.48) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL20924923 | 0.78 | MAPT (0.56) | MAPTTDP1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169958-A | Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-08 | — | — | US | disclosed |