SCHEMBL9724019

SCHEMBL9724019

NC(=O)CCC(NCCCO)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.42
ALOX15 P16050 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
NOD1 Q9Y239 1/20 0.42
GGT1 P19440 2/20 0.41
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
CA2 P00918 4/20 0.38
CA1 P00915 3/20 0.38
FOLH1 Q04609 3/20 0.36
RIMKLA Q8IXN7 1/20 0.36
NAALAD2 Q9Y3Q0 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TGFBR1 P36897 1/20 0.35
CPB2 Q96IY4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002209 1.00 KMT2A (0.42) KMT2AALOX15BLMPMP22NOD1
SCHEMBL3652208 0.95 NOD1 (0.44) KMT2AALOX15BLMPMP22NOD1
SCHEMBL5965370 0.95 NOD1 (0.44) KMT2AALOX15BLMPMP22NOD1
SCHEMBL2250278 0.93 NOD1 (0.46) KMT2AALOX15BLMPMP22NOD1
SCHEMBL2254243 0.93 NOD1 (0.46) KMT2AALOX15BLMPMP22NOD1
SCHEMBL22042 0.89 KMT2A (0.45) KMT2AALOX15BLMPMP22NOD1
SCHEMBL6156358 0.89 KMT2A (0.45) KMT2AALOX15BLMPMP22NOD1
SCHEMBL1226472 0.89 KMT2A (0.45) KMT2AALOX15BLMPMP22NOD1
SCHEMBL3366485 0.88 NOD1 (0.46) KMT2AALOX15BLMPMP22NOD1
SCHEMBL27546911 0.88 NOD1 (0.46) KMT2AALOX15BLMPMP22NOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105440222-B A kind of polyaminoacid nonionic macromolecules cross-linking agent and preparation method thereof 宁波大学 2018-10-02 CN claimed
US-10609922-B2 Protection of progenitor cells and regulation of their differentiation PROTEOBIOACTIVES PTY LTD (AU) 2020-04-07 US disclosed
CN-105440222-B A kind of polyaminoacid nonionic macromolecules cross-linking agent and preparation method thereof 宁波大学 2018-10-02 CN disclosed
US-20180206480-A1 PROTECTION OF PROGENITOR CELLS AND REGULATION OF THEIR DIFFERENTIATION PROTEOBIOACTIVES PTY LTD (AU) 2018-07-26 US disclosed
CN-103725646-A Protection of progenitor cells and regulation of their differentiation PROTEOBIOACTIVES PTY LTD 2014-04-16 CN disclosed
CN-101939417-B Protection of progenitor cells and modulation of their differentiation PROTEOBIOACTIVES PTY LTD 2014-02-05 CN disclosed
CN-101939417-A Protection of progenitor cells and modulation of their differentiation PROTEOBIOACTIVES PTY LTD 2011-01-05 CN disclosed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN disclosed
US-5087616-A Linked by biodegradable polymer to epidermal growth factor BATTELLE MEMORIAL INSTITUTE (CH) 1992-02-11 US disclosed
EP-0259904-B1 ADVANCED ANTICANCER THERAPY AND CYTOTOXIC MEDICAMENTS FOR ITS IMPLEMENTATION IntraCel Corporation (BB) 1991-06-12 EP disclosed
EP-0259904-A1 Advanced anticancer therapy and cytotoxic medicaments for its implementation IntraCel Corporation (BB) 1988-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10609922-B2 Protection of progenitor cells and regulation of their differentiation CD44, MCL1, NES KMT2A 2675/4885ALOX15 2673/4885BLM 3930/4885
US-20180206480-A1 PROTECTION OF PROGENITOR CELLS AND REGULATION OF THEIR DIFFERENTIATION CD44, MCL1, NES KMT2A 2675/4885ALOX15 2673/4885BLM 3930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.