Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 6/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27546911 | 1.00 | NOD1 (0.46) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL27520098 | 0.96 | NOD1 (0.48) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL3362076 | 0.96 | NOD1 (0.48) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL27546900 | 0.92 | NOD1 (0.42) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL3364090 | 0.92 | NOD1 (0.42) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL9724019 | 0.88 | KMT2A (0.42) | NOD1KMT2AALOX15BLMPMP22 | |
| SCHEMBL1002209 | 0.88 | KMT2A (0.42) | NOD1KMT2AALOX15BLMPMP22 | |
| SCHEMBL7759622 | 0.84 | NOD1 (0.57) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL3652208 | 0.84 | NOD1 (0.44) | NOD1ITGB3ITGA2BKMT2AALOX15 | |
| SCHEMBL7759612 | 0.84 | NOD1 (0.57) | NOD1ITGB3ITGA2BKMT2AALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100145018-A1 | Lipid-Polymer-Conjugates | ASTELLAS PHARMA EUROPE BV (NL) | 2010-06-10 | — | — | US | disclosed |
| EP-1392755-B1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | ASTELLAS PHARMA EUROP B V (NL) | 2008-12-03 | — | — | EP | disclosed |
| EP-1392756-B1 | LIPID-POLYMER-CONJUGATES | ASTELLAS PHARMA EUROP B V (NL) | 2007-02-14 | — | — | EP | disclosed |
| US-20040241222-A1 | Lipid-polymer-conjugates compositions | ASTELLAS PHARMA EUROPE B.V. (NL) | 2004-12-02 | — | — | US | disclosed |
| EP-1392755-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2004-03-03 | — | — | EP | disclosed |
| EP-1392756-A2 | LIPID-POLYMER-CONJUGATES | Yamanouchi Europe B.V. (NL) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002098952-A1 | LIPID-POLYMER-CONJUGATES COMPOSITIONS | YAMANOUCHI EUROPE B.V. (NL) | 2002-12-12 | — | — | WO | disclosed |
| WO-2002098951-A2 | LIPID-POLYMER-CONJUGATES | YAMANOUCHI EUROPE B.V. (NL) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145018-A1 | Lipid-Polymer-Conjugates | PARG, GLUL, PHOSPHO1 | NOD1 4449/4885ITGB3 2109/4885ITGA2B 2339/4885 |
| US-20040241222-A1 | Lipid-polymer-conjugates compositions | PHOSPHO1, PARG, GLUL | NOD1 4350/4885ITGB3 2192/4885ITGA2B 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.