Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.39 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724032 | 0.85 | KMT2A (0.38) | TSHRMAPK1RECQLKMT2ASMN1; SMN2 | |
| SCHEMBL9386772 | 0.83 | KMT2A (0.40) | TSHRKMT2AP2RX7LMNASMN1; SMN2 | |
| SCHEMBL9724044 | 0.82 | P2RX7 (0.36) | TSHRKMT2AP2RX7LMNASMN1; SMN2 | |
| SCHEMBL9724034 | 0.81 | KMT2A (0.50) | TSHRKMT2ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8877689 | 0.80 | TSHR (0.42) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL9727236 | 0.80 | TSHR (0.57) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL8877593 | 0.80 | TSHR (0.42) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL8876826 | 0.80 | TSHR (0.46) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL8875871 | 0.80 | TSHR (0.41) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL8875647 | 0.79 | TSHR (0.45) | TSHRMAPK1RECQLKMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116836-A | Herbicides, insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |