Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8877593 | 0.88 | TSHR (0.42) | TSHRMAPK1RECQLKMT2ADPP4 | |
| SCHEMBL8877689 | 0.88 | TSHR (0.42) | TSHRMAPK1RECQLKMT2ADPP4 | |
| SCHEMBL8878241 | 0.86 | KMT2A (0.38) | TSHRMAPK1RECQLKMT2ADPP4 | |
| SCHEMBL8317634 | 0.84 | KMT2A (0.40) | TSHRRECQLKMT2ADPP4P2RX7 | |
| SCHEMBL8876826 | 0.83 | TSHR (0.46) | TSHRMAPK1RECQLKMT2ADPP4 | |
| SCHEMBL8877111 | 0.83 | ALDH1A1 (0.37) | TSHRKMT2AP2RX7LMNASMN1; SMN2 | |
| SCHEMBL8875647 | 0.82 | TSHR (0.45) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL8875704 | 0.81 | KMT2A (0.49) | TSHRKMT2AHTTLMNASMN1; SMN2 | |
| SCHEMBL9727236 | 0.80 | TSHR (0.57) | TSHRMAPK1RECQLKMT2AP2RX7 | |
| SCHEMBL9724043 | 0.80 | TSHR (0.42) | TSHRMAPK1RECQLKMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693663-A | PESTICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5585384-A | 1-OXY-FUNCTIONAL GROUP-2-ALKYLARYL-3-OXO-PYRROLIZINES; INSECTICIDES; NEMATOCIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-12-17 | — | — | US | disclosed |
| US-5288874-A | Insecticides, miticides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-02-22 | — | — | US | disclosed |