Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.36 |
| ▸ | SELE | P16581 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | TYMS | P04818 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489008 | 0.81 | MAPT (0.39) | HAO1TERTICAM1SELENOTUM | |
| SCHEMBL9724080 | 0.79 | KDM4E (0.51) | ALDH1A1TERTNOTUMUSP7DHFR | |
| SCHEMBL9373023 | 0.74 | APP (0.38) | ALDH1A1MAPTCYP2A6KDM4EPKM | |
| SCHEMBL9724212 | 0.72 | ALDH1A1 (0.50) | ALDH1A1HAO1TERTNOTUMUSP7 | |
| SCHEMBL9724103 | 0.71 | ALDH1A1 (0.39) | ALDH1A1ICAM1SELELMNAMAPT | |
| SCHEMBL7593054 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HAO1TERTICAM1SELE | |
| SCHEMBL20535403 | 0.70 | TDP1 (0.53) | ALDH1A1HAO1TERTICAM1SELE | |
| SCHEMBL28963672 | 0.70 | ALDH1A1 (0.38) | ALDH1A1NOTUMUSP7LMNAMAPT | |
| SCHEMBL9724087 | 0.70 | NOTUM (0.40) | NOTUMMAPTGRM5KDM4E | |
| SCHEMBL10957865 | 0.70 | HAO1 (0.53) | HAO1NOTUMLMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |