Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489008 | 0.80 | MAPT (0.39) | L3MBTL1TERTUSP7MEN1KMT2A | |
| SCHEMBL9373023 | 0.80 | APP (0.38) | KDM4EPKML3MBTL1HSD17B1HSD17B2 | |
| SCHEMBL9724142 | 0.79 | ALDH1A1 (0.39) | KDM4EPKML3MBTL1TERTUSP7 | |
| SCHEMBL9724087 | 0.78 | NOTUM (0.40) | KDM4EHPGDKMT2ANOTUMPOLB | |
| SCHEMBL17398498 | 0.77 | RHEB (0.41) | KDM4EPKML3MBTL1TERTUSP7 | |
| SCHEMBL17398433 | 0.75 | SLC6A2 (0.42) | KDM4EPKML3MBTL1TERTUSP7 | |
| SCHEMBL11392906 | 0.74 | HSD17B1 (0.52) | KDM4EPKML3MBTL1USP7HSD17B1 | |
| SCHEMBL11521691 | 0.73 | L3MBTL1 (0.68) | KDM4EPKML3MBTL1USP7HSD17B1 | |
| SCHEMBL5804507 | 0.73 | CA2 (0.49) | KDM4EPKML3MBTL1MEN1ALDH1A1 | |
| SCHEMBL9724133 | 0.73 | USP7 (0.60) | KDM4EPKML3MBTL1USP7HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |