Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31351864 | 0.86 | FBP1 (0.52) | PDE7AKDM4EPKML3MBTL1FBP1 | |
| SCHEMBL6778047 | 0.79 | FBP1 (0.48) | PDE7AKDM4EL3MBTL1FBP1KMT2A | |
| SCHEMBL9724099 | 0.78 | PDE7A (0.44) | PDE7AL3MBTL1FBP1GRM5LMNA | |
| SCHEMBL28656445 | 0.78 | FBP1 (0.43) | PDE7AKDM4EFBP1ALDH1A1CYP1A2 | |
| SCHEMBL30688805 | 0.77 | POLB (0.56) | KDM4EPKML3MBTL1FBP1KMT2A | |
| SCHEMBL29543630 | 0.77 | POLB (0.56) | KDM4EPKML3MBTL1FBP1KMT2A | |
| SCHEMBL2282611 | 0.77 | POLB (0.56) | KDM4EPKML3MBTL1FBP1KMT2A | |
| SCHEMBL588852 | 0.76 | FBP1 (0.54) | PDE7AKDM4EPKML3MBTL1FBP1 | |
| SCHEMBL10596007 | 0.75 | POLB (0.55) | KDM4EPKML3MBTL1FBP1KMT2A | |
| Hydrogen Sulfide SCHEMBL2786811 | 0.74 | FBP1 (0.52) | PDE7AKDM4EPKML3MBTL1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |