Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.44 |
| ▸ | FBP1 | P09467 | 2/20 | 0.43 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778047 | 0.79 | FBP1 (0.48) | PDE7AFBP1HAO1L3MBTL1MAPT | |
| SCHEMBL31351864 | 0.78 | FBP1 (0.52) | PDE7AFBP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL9724157 | 0.78 | PDE7A (0.48) | PDE7AFBP1GRM5L3MBTL1LMNA | |
| SCHEMBL9084641 | 0.76 | ALDH1A1 (0.46) | PDE7AFBP1HAO1MAPTSMN1; SMN2 | |
| SCHEMBL10957865 | 0.75 | HAO1 (0.53) | PDE7AFBP1GRM5HAO1MAPT | |
| SCHEMBL11729689 | 0.74 | KCNH2 (0.46) | PDE7AFBP1SMN1; SMN2TDP1NPC1 | |
| SCHEMBL2432241 | 0.72 | FBP1 (0.68) | PDE7AFBP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL588852 | 0.71 | FBP1 (0.54) | PDE7AFBP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL2787500 | 0.71 | NR1H2 (0.52) | PDE7AFBP1L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL6772507 | 0.71 | FBP1 (0.48) | PDE7AFBP1MAPTSMN1; SMN2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |