Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SOAT1 | P35610 | 9/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483811 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CA2SOAT1GPR84PTGS2 | |
| SCHEMBL11720811 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CA2SOAT1GPR84PTGS2 | |
| SCHEMBL11713091 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CA2SOAT1GPR84PTGS2 | |
| SCHEMBL11711430 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CA2SOAT1GPR84PTGS2 | |
| SCHEMBL11713052 | 0.98 | ALDH1A1 (0.42) | ALDH1A1CA2SOAT1GPR84PTGS2 | |
| SCHEMBL4724956 | 0.95 | ALDH1A1 (0.45) | ALDH1A1CA2SOAT1SERPINE1PTGS2 | |
| SCHEMBL7361138 | 0.81 | SERPINE1 (0.44) | ALDH1A1CA2SERPINE1 | |
| SCHEMBL9147061 | 0.81 | CA2 (0.36) | ALDH1A1CA2SERPINE1 | |
| SCHEMBL8633515 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SERPINE1 | |
| SCHEMBL11717234 | 0.80 | CA2 (0.35) | ALDH1A1CA2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158971-A | Antiallergens, antiinflammatory agents | LILLY INDUSTRIES LIMITED (GB) | 1992-10-27 | — | — | US | disclosed |
| EP-0459748-A2 | Thien-2-yl methylurea derivatives as leukotriene inhibitors | LILLY INDUSTRIES LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |