Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | EDNRA | P25101 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724299 | 0.86 | HPGD (0.56) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL9724233 | 0.85 | SMN1; SMN2 (0.55) | HPGDLMNAALDH1A1SMPD1HDAC1 | |
| SCHEMBL28511377 | 0.83 | HPGD (0.55) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL4599529 | 0.82 | SMPD1 (0.54) | HPGDLMNASMPD1HDAC1HDAC8 | |
| SCHEMBL19610526 | 0.79 | HPGD (0.57) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL24983636 | 0.78 | LMNA (0.58) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL2338199 | 0.78 | HPGD (0.76) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL31644614 | 0.78 | LMNA (0.58) | HPGDLMNAUSP2ALDH1A1TSHR | |
| SCHEMBL7281267 | 0.77 | CLCN2 (0.55) | HPGDLMNAALDH1A1SMPD1HDAC1 | |
| SCHEMBL5503391 | 0.77 | NCEH1 (0.59) | HPGDLMNAUSP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166208-A | Antitumor agents; antibiotics | BOSTON COLLEGE (US) | 1992-11-24 | — | — | US | disclosed |