Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724299 | 0.86 | HPGD (0.56) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL9724243 | 0.85 | HPGD (0.57) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL2761617 | 0.81 | EDNRA (0.54) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL4599529 | 0.79 | SMPD1 (0.54) | SMN1; SMN2HPGDLMNASMPD1HDAC1 | |
| SCHEMBL5120937 | 0.79 | CA12 (0.59) | MAPTTDP1L3MBTL1HPGDLMNA | |
| SCHEMBL31643786 | 0.78 | MAPT (0.53) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL28448203 | 0.78 | HPGD (0.71) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL25246749 | 0.77 | MEN1 (0.55) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 | |
| SCHEMBL7281267 | 0.77 | CLCN2 (0.55) | SMN1; SMN2CYP2C9CYP2C19HPGDLMNA | |
| SCHEMBL24379079 | 0.77 | LMNA (0.55) | SMN1; SMN2MAPTCYP2C9CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166208-A | Antitumor agents; antibiotics | BOSTON COLLEGE (US) | 1992-11-24 | — | — | US | disclosed |