Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2190383 | 0.75 | EPHX2 (0.39) | GRM2EPHX2HSD11B1EPHX1CYP2C9 | |
| SCHEMBL2194681 | 0.75 | EPHX2 (0.39) | GRM2EPHX2HSD11B1EPHX1CYP2C9 | |
| SCHEMBL22073526 | 0.72 | CYP2C9 (0.35) | EPHX2CYP2C9 | |
| Adamantane SCHEMBL28647589 | 0.67 | GRM2 (0.41) | GRM2EPHX2HSD11B1EPHX1GRM3 | |
| SCHEMBL6456147 | 0.67 | CYP2C9 (0.41) | EPHX2HSD11B1EPHX1CYP2C9 | |
| SCHEMBL25660661 | 0.67 | GRM2 (0.63) | GRM2GRM3 | |
| SCHEMBL2196303 | 0.67 | HSD11B1 (0.38) | GRM2EPHX2HSD11B1EPHX1L3MBTL1 | |
| SCHEMBL4067305 | 0.66 | CYP2C9 (0.38) | EPHX2EPHX1CYP2C9 | |
| SCHEMBL10322394 | 0.66 | EPHX2 (0.35) | EPHX2HSD11B1EPHX1MAPT | |
| SCHEMBL4513896 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134121-A | Blocking peptides; therapy for nervous sytem disorders | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-07-28 | — | — | US | disclosed |
| WO-1989009225-A1 | NERVE GROWTH FACTOR PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-10-05 | — | — | WO | disclosed |
| EP-0335637-A2 | Nerve growth factor peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1989-10-04 | — | — | EP | disclosed |