Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194681 | 0.75 | EPHX2 (0.39) | HSD11B1L3MBTL1GRM2EPHX2EPHX1 | |
| Adamantane SCHEMBL28647589 | 0.68 | GRM2 (0.41) | HSD11B1GRM2GRM3EPHX2EPHX1 | |
| SCHEMBL6346244 | 0.67 | CYP2C9 (0.36) | HSD11B1L3MBTL1EPHX2EPHX1 | |
| SCHEMBL2190383 | 0.67 | EPHX2 (0.39) | HSD11B1L3MBTL1GRM2EPHX2EPHX1 | |
| SCHEMBL9724279 | 0.67 | GRM2 (0.47) | HSD11B1L3MBTL1GRM2GRM3EPHX2 | |
| SCHEMBL15910722 | 0.66 | L3MBTL1 (0.35) | HSD11B1L3MBTL1EPHX2EPHX1 | |
| SCHEMBL11365396 | 0.65 | KEAP1 (0.38) | GRM2GRM3EPHX1 | |
| SCHEMBL15910721 | 0.64 | EPHX2 (0.34) | HSD11B1L3MBTL1EPHX2EPHX1 | |
| SCHEMBL13144964 | 0.63 | EPHX2 (0.37) | HSD11B1L3MBTL1EPHX2EPHX1 | |
| SCHEMBL2196307 | 0.63 | GRM2 (0.36) | HSD11B1GRM2GRM3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522868-B2 | Tetrakis(ether-substituted formylphenyl) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-20160016884-A1 | NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2016-01-21 | — | — | US | disclosed |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20090068586-A1 | SILSESQUIOXANE RESIN, POSITIVE RESIST COMPOSITION, RESIST LAMINATE, AND METHOD OF FORMING RESIST PATTERN | TOKYO OHKA KOGYO CO., LTD. (JP) | 2009-03-12 | — | — | US | disclosed |
| US-20060222866-A1 | Silsesquioxane resin, positive resist composition,layered product including resist and method of forming resist pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016884-A1 | NEW TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) | AHR, PAH, ALK | HSD11B1 699/4885L3MBTL1 3045/4885GRM2 2100/4885 |
| US-20110172457-A1 | TETRAKIS(ETHER-SUBSTITUTED FORMYLPHENYL) AND NEW POLYNUCLEAR POLYPHENOL DERIVED FROM THE SAME | AHR, PAH, ARNT | HSD11B1 3313/4885L3MBTL1 4237/4885GRM2 2238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.