SCHEMBL9724371

SCHEMBL9724371

CC(C)=COC(=O)CC(C)C(=O)OC=C(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
PRKCA P17252 2/20 0.33
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28251477 0.85 ALDH1A1 (0.44) TSHRALDH1A1TDP1PRKCAALOX15
SCHEMBL8003214 0.77
SCHEMBL8469000 0.75 TSHR (0.33) TSHRTDP1
SCHEMBL10011645 0.73 TSHR (0.36) TSHRTDP1
SCHEMBL3205875 0.73 TSHR (0.38) TSHRALDH1A1TDP1ALOX15
SCHEMBL3019997 0.72 TSHR (0.37) TSHRALDH1A1TDP1ALOX15
SCHEMBL8916573 0.71 MGAM (0.38) TSHRALDH1A1
SCHEMBL446877 0.71 TSHR (0.41) TSHRALDH1A1ALOX15
SCHEMBL8526100 0.69
SCHEMBL27445719 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5118835-A Stable sludge dispersants, varnish inhibitors, antioxidants, wear resistance for lubricating oil and fuels EXXON RESEARCH & ENGINEERING CO. (US) 1992-06-02 US disclosed
US-4965375-A ANTIDEPOSIT AGENTS EXXON RESEARCH AND ENGINEERING CO. (US) 1990-10-23 US disclosed
US-4866187-A ADDUCT OF SULFUR CHLORIDE, POLYISOBUTYLENE SUCCINIC ANHYDRIDE, AND TRIPENTAERYTHRITOL EXXON RESEARCH & ENGINEERING COMPANY (US) 1989-09-12 US disclosed
US-4851524-A SLUDGE DISPERSANTS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-07-25 US disclosed
US-4568756-A Thio-bis-(alkyl lactone acid esters) and thio-bis-(hydrocarbyl diacid esters) are useful additives for lubricating compositions EXXON RESEARCH & ENGINEERING CO. (US) 1986-02-04 US disclosed
US-4417062-A SLUDGE DISPERSANTS; VARNISHES; HEAT, OXIDATION AND WEAR RESISTANCES; FUEL ADDITIVES EXXON RESEARCH & ENGINEERING CO. (US) 1983-11-22 US disclosed
US-4391981-A OIL AND FUEL ADDITIVES EXXON RESEARCH & ENGINEERING CO. (US) 1983-07-05 US disclosed
US-4302395-A Lactone oxazolines as oleaginous additives EXXON RESEARCH & ENGINEERING CO. (US) 1981-11-24 US disclosed
US-4239636-A SLUDGE DISPERSANTS EXXON RESEARCH & ENGINEERING CO. (US) 1980-12-16 US disclosed
US-4221720-A OIL AND FUEL ADDITIVES, ANTI-RUST AGENTS, SLUDGE DISPERSANTS EXXON RESEARCH & ENGINEERING CO. (US) 1980-09-09 US disclosed
US-4174322-A Thiobis(oxazolines) EXXON RESEARCH & ENGINEERING CO. (US) 1979-11-13 US disclosed
US-4167514-A SULDGE DISPERSANTS IN FUELS AND OILS, ANTIRUST AGENTS EXXON RESEARCH & ENGINEERING CO. (US) 1979-09-11 US disclosed
US-4062786-A Lactone oxazolines as oleaginous additives EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-12-13 US disclosed