Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399662 | 0.86 | LMNA (0.59) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL969758 | 0.84 | GAA (0.70) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL4082027 | 0.84 | GAA (0.51) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL30094539 | 0.84 | GAA (0.70) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL30094581 | 0.83 | GAA (0.53) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL3759057 | 0.83 | GAA (0.53) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL17653849 | 0.83 | EPHX2 (0.52) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL3659918 | 0.83 | GAA (0.50) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL7598558 | 0.81 | GAA (0.49) | GAAALDH1A1TSHRNFKB1TDP1 | |
| SCHEMBL24802444 | 0.80 | GAA (0.47) | GAAALDH1A1TSHRNFKB1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158948-A | Treating neurological and psychological disorders | ABBOTT LABORATORIES (US) | 1992-10-27 | — | — | US | disclosed |