Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.44 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24802442 | 0.87 | GAA (0.47) | GAAPOLBALDH1A1HPGDTSHR | |
| SCHEMBL10948188 | 0.87 | LMNA (0.56) | GAAALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL2406042 | 0.83 | CCR5 (0.53) | GAAALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL969758 | 0.81 | GAA (0.70) | GAAPOLBALDH1A1HPGDTSHR | |
| SCHEMBL4082027 | 0.81 | GAA (0.51) | GAAALDH1A1HPGDTSHRNFKB1 | |
| SCHEMBL30094539 | 0.81 | GAA (0.70) | GAAPOLBALDH1A1HPGDTSHR | |
| SCHEMBL12191688 | 0.81 | L3MBTL1 (0.50) | GAAALDH1A1HPGDTSHRNFKB1 | |
| SCHEMBL24803693 | 0.80 | GAA (0.44) | GAAPOLBALDH1A1TSHRNFKB1 | |
| SCHEMBL29180811 | 0.80 | LMNA (0.47) | GAAPOLBALDH1A1HPGDTSHR | |
| SCHEMBL30772156 | 0.80 | GAA (0.44) | GAAPOLBALDH1A1TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268209-A1 | DERIVATIVE HAVING PYRIMIDINE-FUSED CYCLIC STRUCTURE, AND USE THEREOF | 四川汇宇制药股份有限公司 | 2022-12-29 | — | — | WO | disclosed |