SCHEMBL972461

SCHEMBL972461

OCCCOCCCOc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.65
RECQL P46063 1/20 0.65
KCNA3 P22001 1/20 0.60
HDAC1 Q13547 2/20 0.48
HDAC2 Q92769 2/20 0.48
HDAC3 O15379 1/20 0.48
HDAC4 P56524 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
HDAC9 Q9UKV0 1/20 0.48
HDAC5 Q9UQL6 1/20 0.48
DRD2 P14416 1/20 0.48
DRD4 P21917 1/20 0.48
DRD3 P35462 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
LTA4H P09960 2/20 0.47
HTR1B P28222 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5173415 1.00 ALDH1A1 (0.65) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL10389911 0.98 ALDH1A1 (0.63) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL9327528 0.96 KCNA3 (0.67) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL9327512 0.94 ALDH1A1 (0.63) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL9519241 0.94 KCNA3 (0.64) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL10390291 0.92 ALDH1A1 (0.72) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL5175807 0.92 KCNA3 (0.67) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL5174921 0.92 KCNA3 (0.67) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL50192 0.91 ALDH1A1 (0.77) ALDH1A1RECQLKCNA3HDAC1HDAC2
SCHEMBL2844283 0.89 KCNA3 (0.75) ALDH1A1RECQLKCNA3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0254412-B1 LOW TOXICITY OIL COMPOSITION AND USE THEREOF IN DRILLING FLUIDS BP Chemicals Limited (GB) 1992-02-26 EP claimed
EP-0330379-A2 Cleansing compositions The British Petroleum Company p.l.c. (GB) 1989-08-30 EP claimed
US-4839096-A WITH POLAR ACTIVATOR OF ALIPHATIC ETHERS, AROMATIC ETHERS OR MIXTURES BP CHEMICALS LIMITED (GB) 1989-06-13 US claimed
EP-0254412-A2 Low toxicity oil composition and use thereof in drilling fluids BP Chemicals Limited (GB) 1988-01-27 EP claimed
US-10723717-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides ARVINAS OPERATIONS, INC. (US) 2020-07-28 US disclosed
EP-2259137-B1 METHOD FOR PRODUCING A OF LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2016-08-31 EP disclosed
US-8173585-B2 Acidic hard surface cleaning compositions RECKITT BENCKISER (UK) LIMITED (GB) 2012-05-08 US disclosed
US-20110168044-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2011-07-14 US disclosed
EP-2330464-A1 PROCESS FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM Corporation (JP) 2011-06-08 EP disclosed
US-20110112006-A1 IMPROVEMENTS IN ACIDIC HARD SURFACE CLEANING COMPOSITIONS RECKITT BENCKISER (UK) LIMITED (GB) 2011-05-12 US disclosed
US-20110020751-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRODUCTION PROCESS OF LITHOGRAPHIC PRINTING PLATE USING THE PRECURSOR FUJIFILM CORPORATION (JP) 2011-01-27 US disclosed
EP-2259137-A1 ORIGINAL PLATE FOR LITHOGRAPHIC PRINTING PLATE, AND METHOD FOR PRODUCTION OF LITHOGRAPHIC PRINTING PLATE USING THE SAME FUJIFILM Corporation (JP) 2010-12-08 EP disclosed
EP-1734106-A1 Cleaning composition and method Reckitt Benckiser (UK) LIMITED (GB) 2006-12-20 EP disclosed
EP-1713893-A1 COMPOSITION AND METHOD Reckitt Benckiser Healthcare (UK) Limited (GB) 2006-10-25 EP disclosed
WO-2006021303-A1 IMIDAZOLIUM-METHYL SULFITES FOR USE AS STARTING COMPOUNDS FOR PRODUCING IONIC LIQUIDS BASF AKTIENGESELLSCHAFT (DE) 2006-03-02 WO disclosed
WO-2005078057-A1 COMPOSITION AND METHOD RECKITT BENCKISER (UK) LIMITED (GB) 2005-08-25 WO disclosed
EP-0254412-B1 LOW TOXICITY OIL COMPOSITION AND USE THEREOF IN DRILLING FLUIDS BP Chemicals Limited (GB) 1992-02-26 EP disclosed
EP-0330379-A2 Cleansing compositions The British Petroleum Company p.l.c. (GB) 1989-08-30 EP disclosed
US-4839096-A WITH POLAR ACTIVATOR OF ALIPHATIC ETHERS, AROMATIC ETHERS OR MIXTURES BP CHEMICALS LIMITED (GB) 1989-06-13 US disclosed
EP-0254412-A2 Low toxicity oil composition and use thereof in drilling fluids BP Chemicals Limited (GB) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10723717-B2 Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides CRBN, ARAF, VHL ALDH1A1 2833/4885RECQL 501/4885KCNA3 4805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.